Cargando…

Increased A20-E3 ubiquitin ligase interactions in bid-deficient glia attenuate TLR3- and TLR4-induced inflammation

BACKGROUND: Chronic pro-inflammatory signaling propagates damage to neural tissue and affects the rate of disease progression. Increased activation of Toll-like receptors (TLRs), master regulators of the innate immune response, is implicated in the etiology of several neuropathologies including amyo...

Descripción completa

Detalles Bibliográficos
Autores principales: Kinsella, Sinéad, Fichtner, Michael, Watters, Orla, König, Hans-Georg, Prehn, Jochen H. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5930864/
https://www.ncbi.nlm.nih.gov/pubmed/29720226
http://dx.doi.org/10.1186/s12974-018-1143-3