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Paeoniflorin inhibits glioblastoma growth in vivo and in vitro: a role for the Triad3A-dependent ubiquitin proteasome pathway in TLR4 degradation

BACKGROUND: Paeoniflorin, a polyphenolic compound derived from Radix Paeoniae Alba (Paeonia lactiflora), has exhibited anticancer activity in various human cancers, including glioblastoma. However, the mechanisms underlying the effects of this compound have not been fully elucidated. Toll-like recep...

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Detalles Bibliográficos
Autores principales: Wang, Zhaotao, Yu, Guoyong, Liu, Zhi, Zhu, Jianwei, Chen, Chen, Liu, Ru-en, Xu, Ruxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931203/
https://www.ncbi.nlm.nih.gov/pubmed/29740218
http://dx.doi.org/10.2147/CMAR.S160292