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Rad GTPase Deletion Attenuates Post-Ischemic Cardiac Dysfunction and Remodeling
The protein Rad interacts with the L-type calcium channel complex to modulate trigger Ca(2+) and hence to govern contractility. Reducing Rad levels increases cardiac output. Ablation of Rad also attenuated the inflammatory response following acute myocardial infarction. Future studies to target dele...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931223/ https://www.ncbi.nlm.nih.gov/pubmed/29732439 http://dx.doi.org/10.1016/j.jacbts.2017.09.004 |