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LDH-Apromotes epithelial–mesenchymal transition by upregulating ZEB2 in intestinal-type gastric cancer

INTRODUCTION: Epithelial-mesenchymal transition (EMT) is regarded as a crucial process of invasion and metastasis, which contribute greatly to cancer-related relapse and death. Based on research results that hypoxia can trigger gastric cancer EMT and decreasing lactate production can selectively kil...

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Detalles Bibliográficos
Autores principales: Zhang, Yongjie, Lin, Sen, Chen, Yan, Yang, Fei, Liu, Shenlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931238/
https://www.ncbi.nlm.nih.gov/pubmed/29740212
http://dx.doi.org/10.2147/OTT.S163570