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CD8 (+) T-cell responses in vaccination: reconsidering targets and function in the context of chronic antigen stimulation

Cytotoxic CD8 T cells play important roles in eliminating infected and transformed cells. Owing to their potential for therapeutic applications, significant efforts are dedicated toward developing CD8 T cell–based vaccines. Thus far, CD8 T-cell vaccination strategies have had limited success therape...

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Detalles Bibliográficos
Autores principales: Cosma, Gabriela, Eisenlohr, Laurence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931265/
https://www.ncbi.nlm.nih.gov/pubmed/29770202
http://dx.doi.org/10.12688/f1000research.14115.1