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CD8 (+) T-cell responses in vaccination: reconsidering targets and function in the context of chronic antigen stimulation
Cytotoxic CD8 T cells play important roles in eliminating infected and transformed cells. Owing to their potential for therapeutic applications, significant efforts are dedicated toward developing CD8 T cell–based vaccines. Thus far, CD8 T-cell vaccination strategies have had limited success therape...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000 Research Limited
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931265/ https://www.ncbi.nlm.nih.gov/pubmed/29770202 http://dx.doi.org/10.12688/f1000research.14115.1 |