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Structure of frequency-interacting RNA helicase from Neurospora crassa reveals high flexibility in a domain critical for circadian rhythm and RNA surveillance

The FRH (frequency-interacting RNA helicase) protein is the Neurospora crassa homolog of yeast Mtr4, an essential RNA helicase that plays a central role in RNA metabolism as an activator of the nuclear RNA exosome. FRH is also a required component of the circadian clock, mediating protein interactio...

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Detalles Bibliográficos
Autores principales: Morales, Yalemi, Olsen, Keith J., Bulcher, Jacqueline M., Johnson, Sean J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931499/
https://www.ncbi.nlm.nih.gov/pubmed/29718972
http://dx.doi.org/10.1371/journal.pone.0196642