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N-glycosylation of mouse TRAIL-R restrains TRAIL-induced apoptosis

The sensitivity of cells to death receptor-induced apoptosis is commonly controlled by multiple checkpoints in order to limit induction of excessive or unnecessary death. Although cytotoxic in various cancer cells, tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) does not trigge...

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Detalles Bibliográficos
Autores principales: Estornes, Yann, Dondelinger, Yves, Weber, Kathrin, Bruggeman, Inge, Peall, Adam, MacFarlane, Marion, Lebecque, Serge, Vandenabeele, Peter, Bertrand, Mathieu J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931557/
https://www.ncbi.nlm.nih.gov/pubmed/29717117
http://dx.doi.org/10.1038/s41419-018-0544-7