CCL4 enhances preosteoclast migration and its receptor CCR5 downregulation by RANKL promotes osteoclastogenesis

Chemokine CCL4 (MIP-1β) is released from osteoblast cells to restore the homeostasis of hematopoietic stem cells during the activation of bone marrow. In this study, we investigated the function of CCL4 and its receptor CCR5 during osteoclastogenesis. CCL4 promoted the migration and viability of pre...

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Detalles Bibliográficos
Autores principales: Lee, Dabin, Shin, Kyung-Ju, Kim, Dong Wook, Yoon, Kyung-Ae, Choi, Young-Jin, Lee, Bom Nae Rin, Cho, Je-Yoel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931580/
https://www.ncbi.nlm.nih.gov/pubmed/29717113
http://dx.doi.org/10.1038/s41419-018-0562-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931580/
https://www.ncbi.nlm.nih.gov/pubmed/29717113
http://dx.doi.org/10.1038/s41419-018-0562-5

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