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CCL4 enhances preosteoclast migration and its receptor CCR5 downregulation by RANKL promotes osteoclastogenesis
Chemokine CCL4 (MIP-1β) is released from osteoblast cells to restore the homeostasis of hematopoietic stem cells during the activation of bone marrow. In this study, we investigated the function of CCL4 and its receptor CCR5 during osteoclastogenesis. CCL4 promoted the migration and viability of pre...
Autores principales: | Lee, Dabin, Shin, Kyung-Ju, Kim, Dong Wook, Yoon, Kyung-Ae, Choi, Young-Jin, Lee, Bom Nae Rin, Cho, Je-Yoel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931580/ https://www.ncbi.nlm.nih.gov/pubmed/29717113 http://dx.doi.org/10.1038/s41419-018-0562-5 |
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