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Kinesin light chain-4 depletion induces apoptosis of radioresistant cancer cells by mitochondrial dysfunction via calcium ion influx

Kinesins act as molecular microtubule-dependent motor proteins and have various important cellular functions related to cell division, intracellular transport, and membrane trafficking. However, the function of kinesin light chain 4 (KLC4) in cancer, especially radioresistance, has not been previous...

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Detalles Bibliográficos
Autores principales: Baek, Jeong-Hwa, Lee, Janet, Yun, Hong Shik, Lee, Chang-Woo, Song, Jie-Young, Um, Hong-Duck, Park, Jong Kuk, Park, In-Chul, Kim, Jae-Sung, Kim, Eun Ho, Hwang, Sang-Gu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931584/
https://www.ncbi.nlm.nih.gov/pubmed/29717133
http://dx.doi.org/10.1038/s41419-018-0549-2