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Effect of the sodium–glucose cotransporter 2 inhibitor luseogliflozin on pancreatic beta cell mass in db/db mice of different ages

To examine the effects of luseogliflozin, a sodium–glucose cotransporter 2 inhibitor, on pancreatic beta cell mass in db/db mice of different ages. db/db mice aged 6, 10, 14 and 24 weeks old were fed either standard chow (control group) or standard chow containing 0.01% luseogliflozin (luseo group)....

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Detalles Bibliográficos
Autores principales: Takahashi, Kiyohiko, Nakamura, Akinobu, Miyoshi, Hideaki, Nomoto, Hiroshi, Kitao, Naoyuki, Omori, Kazuno, Yamamoto, Kohei, Cho, Kyu Yong, Terauchi, Yasuo, Atsumi, Tatsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931598/
https://www.ncbi.nlm.nih.gov/pubmed/29717223
http://dx.doi.org/10.1038/s41598-018-25126-z