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Growth differentiation factor 15 ameliorates nonalcoholic steatohepatitis and related metabolic disorders in mice

Growth differentiation factor 15 (GDF15) is an endocrine hormone belonging to the TGFβ superfamily member. GDF15 administration or GDF15 overexpression has been reported to have anti-obesity and anti-diabetic effects. Although non-alcoholic fatty liver disease (NAFLD)/non-alcoholic steatohepatitis (...

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Detalles Bibliográficos
Autores principales: Kim, Kook Hwan, Kim, Seong Hun, Han, Dai Hoon, Jo, Young Suk, Lee, Yong-ho, Lee, Myung-Shik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931608/
https://www.ncbi.nlm.nih.gov/pubmed/29717162
http://dx.doi.org/10.1038/s41598-018-25098-0