Predicting drug resistance related to ABC transporters using unsupervised Consensus Self-Organizing Maps

ATP binding cassette (ABC) transporters play a pivotal role in drug elimination, particularly on several types of cancer in which these proteins are overexpressed. Due to their promiscuous ligand recognition, building computational models for substrate classification is quite challenging. This study...

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Detalles Bibliográficos
Autores principales: Estrada-Tejedor, Roger, Ecker, Gerhard F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931609/
https://www.ncbi.nlm.nih.gov/pubmed/29717183
http://dx.doi.org/10.1038/s41598-018-25235-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931609/
https://www.ncbi.nlm.nih.gov/pubmed/29717183
http://dx.doi.org/10.1038/s41598-018-25235-9

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