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Predicting drug resistance related to ABC transporters using unsupervised Consensus Self-Organizing Maps
ATP binding cassette (ABC) transporters play a pivotal role in drug elimination, particularly on several types of cancer in which these proteins are overexpressed. Due to their promiscuous ligand recognition, building computational models for substrate classification is quite challenging. This study...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931609/ https://www.ncbi.nlm.nih.gov/pubmed/29717183 http://dx.doi.org/10.1038/s41598-018-25235-9 |