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Effective in vivo treatment of acute lung injury with helical, amphipathic peptoid mimics of pulmonary surfactant proteins

Acute lung injury (ALI) leads to progressive loss of breathing capacity and hypoxemia, as well as pulmonary surfactant dysfunction. ALI’s pathogenesis and management are complex, and it is a significant cause of morbidity and mortality worldwide. Exogenous surfactant therapy, even for research purpo...

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Detalles Bibliográficos
Autores principales: Czyzewski, Ann M., McCaig, Lynda M., Dohm, Michelle T., Broering, Lauren A., Yao, Li-Juan, Brown, Nathan J., Didwania, Maruti K., Lin, Jennifer S., Lewis, Jim F., Veldhuizen, Ruud, Barron, Annelise E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931611/
https://www.ncbi.nlm.nih.gov/pubmed/29717157
http://dx.doi.org/10.1038/s41598-018-25009-3