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Effective in vivo treatment of acute lung injury with helical, amphipathic peptoid mimics of pulmonary surfactant proteins
Acute lung injury (ALI) leads to progressive loss of breathing capacity and hypoxemia, as well as pulmonary surfactant dysfunction. ALI’s pathogenesis and management are complex, and it is a significant cause of morbidity and mortality worldwide. Exogenous surfactant therapy, even for research purpo...
Autores principales: | Czyzewski, Ann M., McCaig, Lynda M., Dohm, Michelle T., Broering, Lauren A., Yao, Li-Juan, Brown, Nathan J., Didwania, Maruti K., Lin, Jennifer S., Lewis, Jim F., Veldhuizen, Ruud, Barron, Annelise E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931611/ https://www.ncbi.nlm.nih.gov/pubmed/29717157 http://dx.doi.org/10.1038/s41598-018-25009-3 |
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