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Tauroursodeoxycholic acid (TUDCA) alleviates endoplasmic reticulum stress of nuclear donor cells under serum starvation

Serum starvation is a routine protocol for synchronizing nuclear donor cells to G0/G1 phase during somatic cell nuclear transfer (SCNT). However, abrupt serum deprivation can cause serious stress to the cells cultured in vitro, which might result in endoplasmic reticulum (ER) stress, chromosome dama...

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Detalles Bibliográficos
Autores principales: Zhang, Ying, Qu, Pengxiang, Ma, Xiaonan, Qiao, Fang, Ma, Yefei, Qing, Suzhu, Zhang, Yong, Wang, Yongsheng, Cui, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931650/
https://www.ncbi.nlm.nih.gov/pubmed/29718981
http://dx.doi.org/10.1371/journal.pone.0196785