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An ultrasonic nanobubble-mediated PNP/fludarabine suicide gene system: A new approach for the treatment of hepatocellular carcinoma

OBJECTIVE: The purpose of this study is to generate an ultrasonic nanobubble (NB)-mediated purine nucleoside phosphorylase (PNP)/fludarabine suicide gene system for the treatment of human hepatocellular carcinoma (HCC). METHODS: NBs were prepared from a mixture the phospholipids 1,2-dipalmitoyl-sn-g...

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Detalles Bibliográficos
Autores principales: Zhang, Bo, Chen, Mingna, Zhang, Youming, Chen, Wei, Zhang, Lihua, Chen, Lv
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931662/
https://www.ncbi.nlm.nih.gov/pubmed/29718963
http://dx.doi.org/10.1371/journal.pone.0196686