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An ultrasonic nanobubble-mediated PNP/fludarabine suicide gene system: A new approach for the treatment of hepatocellular carcinoma
OBJECTIVE: The purpose of this study is to generate an ultrasonic nanobubble (NB)-mediated purine nucleoside phosphorylase (PNP)/fludarabine suicide gene system for the treatment of human hepatocellular carcinoma (HCC). METHODS: NBs were prepared from a mixture the phospholipids 1,2-dipalmitoyl-sn-g...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931662/ https://www.ncbi.nlm.nih.gov/pubmed/29718963 http://dx.doi.org/10.1371/journal.pone.0196686 |