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First evidence of SGPL1 expression in the cell membrane silencing the extracellular S1P siren in mammary epithelial cells

The bioactive lipid sphingosine-1-phosphate (S1P) is a main regulator of cell survival, proliferation, motility, and platelet aggregation, and it is essential for angiogenesis and lymphocyte trafficking. In that S1P acts as a second messenger intra- and extracellularly, it might promote cancer progr...

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Detalles Bibliográficos
Autores principales: Engel, Nadja, Adamus, Anna, Frank, Marcus, Kraft, Karin, Kühn, Juliane, Müller, Petra, Nebe, Barbara, Kasten, Annika, Seitz, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931664/
https://www.ncbi.nlm.nih.gov/pubmed/29718989
http://dx.doi.org/10.1371/journal.pone.0196854