Posttranslational modification of a histone-like protein regulates phenotypic resistance to isoniazid in mycobacteria

There is increasing evidence that phenotypically drug-resistant bacteria may be important determinants of antibiotic treatment failure. Using high-throughput imaging, we defined distinct subpopulations of mycobacterial cells that exhibit heritable but semi-stable drug resistance. These subpopulation...

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Detalles Bibliográficos
Autores principales: Sakatos, Alexandra, Babunovic, Gregory H., Chase, Michael R., Dills, Alexander, Leszyk, John, Rosebrock, Tracy, Bryson, Bryan, Fortune, Sarah M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931751/
https://www.ncbi.nlm.nih.gov/pubmed/29732401
http://dx.doi.org/10.1126/sciadv.aao1478

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931751/
https://www.ncbi.nlm.nih.gov/pubmed/29732401
http://dx.doi.org/10.1126/sciadv.aao1478

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