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Posttranslational modification of a histone-like protein regulates phenotypic resistance to isoniazid in mycobacteria
There is increasing evidence that phenotypically drug-resistant bacteria may be important determinants of antibiotic treatment failure. Using high-throughput imaging, we defined distinct subpopulations of mycobacterial cells that exhibit heritable but semi-stable drug resistance. These subpopulation...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Association for the Advancement of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931751/ https://www.ncbi.nlm.nih.gov/pubmed/29732401 http://dx.doi.org/10.1126/sciadv.aao1478 |