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A persulfidation-based mechanism controls aquaporin-8 conductance

Upon engagement of tyrosine kinase receptors, nicotinamide adenine dinucleotide phosphate (NADPH)–oxidases release H(2)O(2) in the extracellular space. We reported previously that aquaporin-8 (AQP8) transports H(2)O(2) across the plasma membrane and is reversibly gated during cell stress, modulating...

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Detalles Bibliográficos
Autores principales: Bestetti, Stefano, Medraño-Fernandez, Iria, Galli, Mauro, Ghitti, Michela, Bienert, Gerd P., Musco, Giovanna, Orsi, Andrea, Rubartelli, Anna, Sitia, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931763/
https://www.ncbi.nlm.nih.gov/pubmed/29732408
http://dx.doi.org/10.1126/sciadv.aar5770