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A persulfidation-based mechanism controls aquaporin-8 conductance
Upon engagement of tyrosine kinase receptors, nicotinamide adenine dinucleotide phosphate (NADPH)–oxidases release H(2)O(2) in the extracellular space. We reported previously that aquaporin-8 (AQP8) transports H(2)O(2) across the plasma membrane and is reversibly gated during cell stress, modulating...
Autores principales: | Bestetti, Stefano, Medraño-Fernandez, Iria, Galli, Mauro, Ghitti, Michela, Bienert, Gerd P., Musco, Giovanna, Orsi, Andrea, Rubartelli, Anna, Sitia, Roberto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931763/ https://www.ncbi.nlm.nih.gov/pubmed/29732408 http://dx.doi.org/10.1126/sciadv.aar5770 |
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