Broad and diverse mechanisms used by deubiquitinase family members in regulating the type I interferon signaling pathway during antiviral responses

The innate immune response conferred by type I interferons is essential for host defense against viral infection but needs to be tightly controlled to avoid immunopathology. We performed a systematic functional screening by CRISPR/Cas9 (clustered regularly interspaced short palindromic repeats/CRISP...

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Detalles Bibliográficos
Autores principales: Liu, Qingxiang, Wu, Yaoxing, Qin, Yunfei, Hu, Jiajia, Xie, Weihong, Qin, F. Xiao-Feng, Cui, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931765/
https://www.ncbi.nlm.nih.gov/pubmed/29732405
http://dx.doi.org/10.1126/sciadv.aar2824

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931765/
https://www.ncbi.nlm.nih.gov/pubmed/29732405
http://dx.doi.org/10.1126/sciadv.aar2824

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