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Repurposing drugs in oncology (ReDO)—selective PDE5 inhibitors as anti-cancer agents
Selective phosphodiesterase 5 inhibitors, including sildenafil, tadalafil and vardenafil, are widely-used in the treatment of erectile dysfunction and pulmonary arterial hypertension. They are also well-known as examples of successful drug repurposing in that they were initially developed for angina...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cancer Intelligence
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931815/ https://www.ncbi.nlm.nih.gov/pubmed/29743944 http://dx.doi.org/10.3332/ecancer.2018.824 |