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SRSF10-mediated IL1RAP alternative splicing regulates cervical cancer oncogenesis via mIL1RAP-NF-κB-CD47 axis

High-risk human papillomavirus oncoproteins E6 and E7 are the major etiological factors of cervical cancer but are insufficient for malignant transformation of cervical cancer. Dysregulated alternative splicing, mainly ascribed to aberrant splicing factor levels and activities, contributes to most c...

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Detalles Bibliográficos
Autores principales: Liu, Fei, Dai, Miao, Xu, Qinyang, Zhu, Xiaolu, Zhou, Yang, Jiang, Shuheng, Wang, Yahui, Ai, Zhihong, Ma, Li, Zhang, Yanli, Hu, Lipeng, Yang, Qin, Li, Jun, Zhao, Shujie, Zhang, Zhigang, Teng, Yincheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931977/
https://www.ncbi.nlm.nih.gov/pubmed/29429992
http://dx.doi.org/10.1038/s41388-017-0119-6