Identification of a pyrophosphate-dependent kinase and its donor selectivity determinants

Almost all kinases utilize ATP as their phosphate donor, while a few kinases utilize pyrophosphate (PPi) instead. PPi-dependent kinases are often homologous to their ATP-dependent counterparts, but determinants of their different donor specificities remain unclear. We identify a PPi-dependent member...

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Detalles Bibliográficos
Autores principales: Nagata, Ryuhei, Fujihashi, Masahiro, Sato, Takaaki, Atomi, Haruyuki, Miki, Kunio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931981/
https://www.ncbi.nlm.nih.gov/pubmed/29720581
http://dx.doi.org/10.1038/s41467-018-04201-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931981/
https://www.ncbi.nlm.nih.gov/pubmed/29720581
http://dx.doi.org/10.1038/s41467-018-04201-z

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