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Identification of a pyrophosphate-dependent kinase and its donor selectivity determinants
Almost all kinases utilize ATP as their phosphate donor, while a few kinases utilize pyrophosphate (PPi) instead. PPi-dependent kinases are often homologous to their ATP-dependent counterparts, but determinants of their different donor specificities remain unclear. We identify a PPi-dependent member...
Autores principales: | Nagata, Ryuhei, Fujihashi, Masahiro, Sato, Takaaki, Atomi, Haruyuki, Miki, Kunio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931981/ https://www.ncbi.nlm.nih.gov/pubmed/29720581 http://dx.doi.org/10.1038/s41467-018-04201-z |
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