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Spectrum of antibacterial activity and mode of action of a novel tris-stilbene bacteriostatic compound

The spectrum of activity and mode of action of a novel antibacterial agent, 135C, was investigated using a range of microbiological and genomic approaches. Compound 135C was active against Gram-positive bacteria with MICs for Staphylococcus aureus ranging from 0.12–0.5 μg/ml. It was largely inactive...

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Detalles Bibliográficos
Autores principales: Man, Nikki Y. T., Knight, Daniel R., Stewart, Scott G., McKinley, Allan J., Riley, Thomas V., Hammer, Katherine A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932035/
https://www.ncbi.nlm.nih.gov/pubmed/29720673
http://dx.doi.org/10.1038/s41598-018-25080-w