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In silico assessment of the conduction mechanism of the Ryanodine Receptor 1 reveals previously unknown exit pathways

The ryanodine receptor 1 is a large calcium ion channel found in mammalian skeletal muscle. The ion channel gained a lot of attention recently, after multiple independent authors published near-atomic cryo electron microscopy data. Taking advantage of the unprecedented quality of structural data, we...

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Detalles Bibliográficos
Autores principales: Heinz, Leonard P., Kopec, Wojciech, de Groot, Bert L., Fink, Rainer H. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932038/
https://www.ncbi.nlm.nih.gov/pubmed/29720700
http://dx.doi.org/10.1038/s41598-018-25061-z