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Modulation of Haemophilus influenzae interaction with hydrophobic molecules by the VacJ/MlaA lipoprotein impacts strongly on its interplay with the airways

Airway infection by nontypeable Haemophilus influenzae (NTHi) associates to chronic obstructive pulmonary disease (COPD) exacerbation and asthma neutrophilic airway inflammation. Lipids are key inflammatory mediators in these disease conditions and consequently, NTHi may encounter free fatty acids d...

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Detalles Bibliográficos
Autores principales: Fernández-Calvet, Ariadna, Rodríguez-Arce, Irene, Almagro, Goizeder, Moleres, Javier, Euba, Begoña, Caballero, Lucía, Martí, Sara, Ramos-Vivas, José, Bartholomew, Toby Leigh, Morales, Xabier, Ortíz-de-Solórzano, Carlos, Yuste, José Enrique, Bengoechea, José Antonio, Conde-Álvarez, Raquel, Garmendia, Junkal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932069/
https://www.ncbi.nlm.nih.gov/pubmed/29720703
http://dx.doi.org/10.1038/s41598-018-25232-y