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Preparation and preclinical evaluation of a (68)Ga-labelled c(RGDfK) conjugate comprising the bifunctional chelator NODIA-Me

BACKGROUND: We recently developed a chelating platform based on the macrocycle 1,4,7-triazacyclononane with up to three, five-membered azaheterocyclic arms for the development of (68)Ga- and (64)Cu-based radiopharmaceuticals. Here, a (68)Ga-labelled conjugate comprising the bifunctional chelator NOD...

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Detalles Bibliográficos
Autores principales: Läppchen, Tilman, Holland, Jason P., Kiefer, Yvonne, Bartholomä, Mark D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932101/
https://www.ncbi.nlm.nih.gov/pubmed/29756024
http://dx.doi.org/10.1186/s41181-018-0043-2