Progressive IgA Nephropathy Is Associated With Low Circulating Mannan-Binding Lectin–Associated Serine Protease-3 (MASP-3) and Increased Glomerular Factor H–Related Protein-5 (FHR5) Deposition

INTRODUCTION: IgA nephropathy (IgAN) is characterized by glomerular deposition of galactose-deficient IgA1 and complement proteins and leads to renal impairment. Complement deposition through the alternative and lectin activation pathways is associated with renal injury. METHODS: To elucidate the co...

Descripción completa

Detalles Bibliográficos
Autores principales: Medjeral-Thomas, Nicholas R., Troldborg, Anne, Constantinou, Nicholas, Lomax-Browne, Hannah J., Hansen, Annette G., Willicombe, Michelle, Pusey, Charles D., Cook, H. Terence, Thiel, Steffen, Pickering, Matthew C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Clinical Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932138/
https://www.ncbi.nlm.nih.gov/pubmed/29725647
http://dx.doi.org/10.1016/j.ekir.2017.11.015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932138/
https://www.ncbi.nlm.nih.gov/pubmed/29725647
http://dx.doi.org/10.1016/j.ekir.2017.11.015

Ejemplares similares