Cargando…

Progressive IgA Nephropathy Is Associated With Low Circulating Mannan-Binding Lectin–Associated Serine Protease-3 (MASP-3) and Increased Glomerular Factor H–Related Protein-5 (FHR5) Deposition

INTRODUCTION: IgA nephropathy (IgAN) is characterized by glomerular deposition of galactose-deficient IgA1 and complement proteins and leads to renal impairment. Complement deposition through the alternative and lectin activation pathways is associated with renal injury. METHODS: To elucidate the co...

Descripción completa

Detalles Bibliográficos
Autores principales:	Medjeral-Thomas, Nicholas R., Troldborg, Anne, Constantinou, Nicholas, Lomax-Browne, Hannah J., Hansen, Annette G., Willicombe, Michelle, Pusey, Charles D., Cook, H. Terence, Thiel, Steffen, Pickering, Matthew C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2017
Materias:	Clinical Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932138/ https://www.ncbi.nlm.nih.gov/pubmed/29725647 http://dx.doi.org/10.1016/j.ekir.2017.11.015

Ejemplares similares

Glomerular Complement Factor H–Related Protein 5 (FHR5) Is Highly Prevalent in C3 Glomerulopathy and Associated With Renal Impairment
por: Medjeral-Thomas, Nicholas R., et al.
Publicado: (2019)

C3 dysregulation due to factor H deficiency is mannan-binding lectin-associated serine proteases (MASP)-1 and MASP-3 independent in vivo
por: Ruseva, M M, et al.
Publicado: (2014)

Mannan binding lectin-associated serine protease-2 (MASP-2) critically contributes to post-ischemic brain injury independent of MASP-1
por: Orsini, Franca, et al.
Publicado: (2016)

Mannan-binding lectin serine protease-2 (MASP-2) in human kidney and its relevance for proteolytic activation of the epithelial sodium channel
por: Zachar, Rikke, et al.
Publicado: (2022)

Circulating complement factor H–related proteins 1 and 5 correlate with disease activity in IgA nephropathy
por: Medjeral-Thomas, Nicholas R., et al.
Publicado: (2017)

The complex formation of MASP-3 with pattern recognition molecules of the lectin complement pathway retains MASP-3 in the circulation
por: Kusakari, Kohei, et al.
Publicado: (2022)

Plasma Lectin Pathway Complement Proteins in Patients With COVID-19 and Renal Disease
por: Medjeral-Thomas, Nicholas R., et al.
Publicado: (2021)

Clinical manifestations of mannan-binding lectin deficiency
por: Thiel, S., et al.
Publicado: (2006)

Polymorphisms in the MASP1 Gene Are Associated with Serum Levels of MASP-1, MASP-3, and MAp44
por: Gytz Ammitzbøll, Christian, et al.
Publicado: (2013)

Factor H-Related (FHR)-1 and FHR-2 Form Homo- and Heterodimers, while FHR-5 Circulates Only As Homodimer in Human Plasma
por: van Beek, Anna E., et al.
Publicado: (2017)

Pentraxin 3, ficolin-2 and lectin pathway associated serine protease MASP-3 as early predictors of myocardial infarction - the HUNT2 study
por: Vengen, Inga Thorsen, et al.
Publicado: (2017)

Flexibility in Mannan-Binding Lectin-Associated Serine Proteases-1 and -2 Provides Insight on Lectin Pathway Activation
por: Nan, Ruodan, et al.
Publicado: (2017)

Diabetes Is Associated with Increased Autoreactivity of Mannan-Binding Lectin
por: Axelgaard, Esben, et al.
Publicado: (2017)

Targeting of Liver Mannan-Binding Lectin–Associated Serine Protease-3 with RNA Interference Ameliorates Disease in a Mouse Model of Rheumatoid Arthritis
por: Banda, Nirmal K., et al.
Publicado: (2018)

Cleavage of Kininogen and Subsequent Bradykinin Release by the Complement Component: Mannose-Binding Lectin-Associated Serine Protease (MASP)-1
por: Dobó, József, et al.
Publicado: (2011)

MBL-associated serine proteases (MASPs) and infectious diseases
por: Beltrame, Marcia H., et al.
Publicado: (2015)

Mannan-binding lectin and procalcitonin measurement for prediction of postoperative infection
por: Siassi, Michael, et al.
Publicado: (2005)

The Serine Protease Domain of MASP-3: Enzymatic Properties and Crystal Structure in Complex with Ecotin
por: Gaboriaud, Christine, et al.
Publicado: (2013)

Interactions between mannose-binding lectin and MASPs during complement activation by the lectin pathway
por: Wallis, Russell
Publicado: (2007)

Mannan-Binding Lectin in Cardiovascular Disease
por: Pągowska-Klimek, Izabela, et al.
Publicado: (2014)

Mannose-Binding Lectin (MBL) and MBL-associated serine protease-2 (MASP-2) in women with malignant and benign ovarian tumours
por: Swierzko, Anna St., et al.
Publicado: (2014)

Leprosy Association with Low MASP-2 Levels Generated by MASP2 Haplotypes and Polymorphisms Flanking MAp19 Exon 5
por: Boldt, Angelica Beate Winter, et al.
Publicado: (2013)

Correction: Mannan-binding lectin and procalcitonin measurement for prediction of postoperative infection
por: Siassi, Michael, et al.
Publicado: (2005)

Interaction of the Factor H Family Proteins FHR-1 and FHR-5 With DNA and Dead Cells: Implications for the Regulation of Complement Activation and Opsonization
por: Kárpáti, Éva, et al.
Publicado: (2020)

Increased Autoreactivity of the Complement-Activating Molecule Mannan-Binding Lectin in a Type 1 Diabetes Model
por: Østergaard, Jakob Appel, et al.
Publicado: (2016)

Mannose-binding lectin-associated serine protease 2 (MASP-2) contributes to poor disease outcome in humans and mice with pneumococcal meningitis
por: Kasanmoentalib, E. Soemirien, et al.
Publicado: (2017)

Serum mannan-binding lectin-associated serine proteases in early pregnancy for gestational diabetes in Chinese pregnant women
por: Gao, Ming, et al.
Publicado: (2023)

Effect of Optimization of Glycaemic Control on Mannan-Binding Lectin in Type 1 Diabetes
por: Dørflinger, Gry Høst, et al.
Publicado: (2017)

Mutations in the lectin complement pathway genes COLEC11 and MASP1 cause 3MC syndrome
por: Rooryck, Caroline, et al.
Publicado: (2011)

Protease inhibitor plasma concentrations associate with COVID-19 infection
por: Medjeral-Thomas, Nicholas R, et al.
Publicado: (2021)

Erratum to: Mannose-binding lectin-associated serine protease 2 (MASP-2) contributes to poor disease outcome in humans and mice with pneumococcal meningitis
por: Kasanmoentalib, E. Soemirien, et al.
Publicado: (2017)

Fasciola hepatica is refractory to complement killing by preventing attachment of mannose binding lectin (MBL) and inhibiting MBL-associated serine proteases (MASPs) with serpins
por: De Marco Verissimo, Carolina, et al.
Publicado: (2022)

Lectin Pathway Enzyme MASP-2 and Downstream Complement Activation in COVID-19
por: Götz, Maximilian Peter, et al.
Publicado: (2022)

Applications of mannose-binding lectins and mannan glycoconjugates in nanomedicine
por: Gupta, Anita, et al.
Publicado: (2022)

Adding MASP1 to the lectin pathway—Leprosy association puzzle: Hints from gene polymorphisms and protein levels
por: Weinschutz Mendes, Hellen, et al.
Publicado: (2020)

Lysyl Hydroxylase 3 Modifies Lysine Residues to Facilitate Oligomerization of Mannan-Binding Lectin
por: Risteli, Maija, et al.
Publicado: (2014)

Prevalence of the polymorphic H-f icolin (FCN3) genes and mannose-binding lectin-associated serine protease-2 (MASP2) in indigenous populations from the Russian Arctic regions
por: Smolnikova, M.V., et al.
Publicado: (2021)

MASP-1 and MASP-2 Serum Levels Are Associated With Worse Prognostic in Cervical Cancer Progression
por: Maestri, Carlos Afonso, et al.
Publicado: (2018)

FHR-5 Serum Levels and CFHR5 Genetic Variations in Patients With Immune Complex-Mediated Membranoproliferative Glomerulonephritis and C3-Glomerulopathy
por: Garam, Nóra, et al.
Publicado: (2021)

Complement Factor H-Related Proteins FHR1 and FHR5 Interact With Extracellular Matrix Ligands, Reduce Factor H Regulatory Activity and Enhance Complement Activation
por: Papp, Alexandra, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_navjai1u6gmmp5rja8927i4mri