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Oncolytic Viral Therapy and the Immune System: A Double-Edged Sword Against Cancer

Oncolytic viral therapy is a new promising strategy against cancer. Oncolytic viruses (OVs) can replicate in cancer cells but not in normal cells, leading to lysis of the tumor mass. Beside this primary effect, OVs can also stimulate the immune system. Tumors are an immuno-suppressive environment in...

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Detalles Bibliográficos
Autores principales: Marelli, Giulia, Howells, Anwen, Lemoine, Nicholas R., Wang, Yaohe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932159/
https://www.ncbi.nlm.nih.gov/pubmed/29755464
http://dx.doi.org/10.3389/fimmu.2018.00866