Integrative Analysis Identifies Genetic Variants Associated With Autoimmune Diseases Affecting Putative MicroRNA Binding Sites

Genome-wide and fine mapping studies have shown that more than 90% of genetic variants associated with autoimmune diseases (AID) are located in non-coding regions of the human genome and especially in regulatory sequences, including microRNAs (miRNA) target sites. MiRNAs are small endogenous noncodi...

Descripción completa

Detalles Bibliográficos
Autores principales: de Almeida, Rodrigo C., Chagas, Vinícius S., Castro, Mauro A. A., Petzl-Erler, Maria L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932181/
https://www.ncbi.nlm.nih.gov/pubmed/29755505
http://dx.doi.org/10.3389/fgene.2018.00139

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932181/
https://www.ncbi.nlm.nih.gov/pubmed/29755505
http://dx.doi.org/10.3389/fgene.2018.00139

Ejemplares similares