The Interplay of Rogue and Clustered Ryanodine Receptors Regulates Ca(2+) Waves in Cardiac Myocytes

Ca(2+) waves in cardiac myocytes can lead to arrhythmias owing to delayed after-depolarisations. Based on Ca(2+) regulation from the junctional sarcoplasmic reticulum (JSR), a mathematical model was developed to investigate the interplay of clustered and rogue RyRs on Ca(2+) waves. The model success...

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Detalles Bibliográficos
Autores principales: Chen, Xudong, Feng, Yundi, Huo, Yunlong, Tan, Wenchang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932313/
https://www.ncbi.nlm.nih.gov/pubmed/29755362
http://dx.doi.org/10.3389/fphys.2018.00393

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932313/
https://www.ncbi.nlm.nih.gov/pubmed/29755362
http://dx.doi.org/10.3389/fphys.2018.00393

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