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Influence of APOE and RNF219 on Behavioral and Cognitive Features of Female Patients Affected by Mild Cognitive Impairment or Alzheimer’s Disease

The risk for Alzheimer’s disease (AD) is associated with the presence of the 𝜀4 allele of Apolipoprotein E (APOE) gene and, recently, with a novel genetic variant of the RNF219 gene. This study aimed at evaluating interactions between APOE-𝜀4 and RNF219/G variants in the modulation of behavioral and...

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Detalles Bibliográficos
Autores principales: Mosca, Alessandra, Sperduti, Samantha, Pop, Viorela, Ciavardelli, Domenico, Granzotto, Alberto, Punzi, Miriam, Stuppia, Liborio, Gatta, Valentina, Assogna, Francesca, Banaj, Nerisa, Piras, Fabrizio, Piras, Federica, Caltagirone, Carlo, Spalletta, Gianfranco, Sensi, Stefano L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932379/
https://www.ncbi.nlm.nih.gov/pubmed/29755337
http://dx.doi.org/10.3389/fnagi.2018.00092