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Voltage Gated Calcium Channel Activation by Backpropagating Action Potentials Downregulates NMDAR Function

The majority of excitatory synapses are located on dendritic spines of cortical glutamatergic neurons. In spines, compartmentalized Ca(2+) signals transduce electrical activity into specific long-term biochemical and structural changes. Action potentials (APs) propagate back into the dendritic tree...

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Detalles Bibliográficos
Autores principales: Theis, Anne-Kathrin, Rózsa, Balázs, Katona, Gergely, Schmitz, Dietmar, Johenning, Friedrich W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932410/
https://www.ncbi.nlm.nih.gov/pubmed/29755321
http://dx.doi.org/10.3389/fncel.2018.00109