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Voltage Gated Calcium Channel Activation by Backpropagating Action Potentials Downregulates NMDAR Function
The majority of excitatory synapses are located on dendritic spines of cortical glutamatergic neurons. In spines, compartmentalized Ca(2+) signals transduce electrical activity into specific long-term biochemical and structural changes. Action potentials (APs) propagate back into the dendritic tree...
Autores principales: | Theis, Anne-Kathrin, Rózsa, Balázs, Katona, Gergely, Schmitz, Dietmar, Johenning, Friedrich W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932410/ https://www.ncbi.nlm.nih.gov/pubmed/29755321 http://dx.doi.org/10.3389/fncel.2018.00109 |
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