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Myosin VI-Dependent Actin Cages Encapsulate Parkin-Positive Damaged Mitochondria

Mitochondrial quality control is essential to maintain cellular homeostasis and is achieved by removing damaged, ubiquitinated mitochondria via Parkin-mediated mitophagy. Here, we demonstrate that MYO6 (myosin VI), a unique myosin that moves toward the minus end of actin filaments, forms a complex w...

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Detalles Bibliográficos
Autores principales: Kruppa, Antonina J., Kishi-Itakura, Chieko, Masters, Thomas A., Rorbach, Joanna E., Grice, Guinevere L., Kendrick-Jones, John, Nathan, James A., Minczuk, Michal, Buss, Folma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932465/
https://www.ncbi.nlm.nih.gov/pubmed/29398621
http://dx.doi.org/10.1016/j.devcel.2018.01.007