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Low Magnitude of Compression Enhances Biosynthesis of Mesenchymal Stem Cells towards Nucleus Pulposus Cells via the TRPV4-Dependent Pathway

Mesenchymal stem cell- (MSC-) based therapy is regarded as a promising tissue engineering strategy to achieve nucleus pulposus (NP) regeneration for the treatment of intervertebral disc degeneration (IDD). However, it is still a challenge to promote the biosynthesis of MSC to meet the requirement of...

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Detalles Bibliográficos
Autores principales: Gan, Yibo, Tu, Bing, Li, Pei, Ye, Jixing, Zhao, Chen, Luo, Lei, Zhang, Chengmin, Zhang, Zetong, Zhu, Linyong, Zhou, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932483/
https://www.ncbi.nlm.nih.gov/pubmed/29765419
http://dx.doi.org/10.1155/2018/7061898