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Immunotherapy with CAR-Modified T Cells: Toxicities and Overcoming Strategies
T cells modified via chimeric antigen receptors (CARs) have emerged as a promising treatment modality. Unparalleled clinical efficacy recently demonstrated in refractory B-cell malignancy has brought this new form of adoptive immunotherapy to the center stage. Nonetheless, its current success has al...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932485/ https://www.ncbi.nlm.nih.gov/pubmed/29850622 http://dx.doi.org/10.1155/2018/2386187 |