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Disruption of the Circadian Clock Alters Antioxidative Defense via the SIRT1-BMAL1 Pathway in 6-OHDA-Induced Models of Parkinson's Disease

Parkinson's disease (PD) is the second most common neurodegenerative disease and is known to involve circadian dysfunction and oxidative stress. Although antioxidative defense is regulated by the molecular circadian clock, few studies have examined their function in PD and their regulation by s...

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Detalles Bibliográficos
Autores principales: Wang, Yali, Lv, Dongjun, Liu, Wenwen, Li, Siyue, Chen, Jing, Shen, Yun, Wang, Fen, Hu, Li-Fang, Liu, Chun-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932489/
https://www.ncbi.nlm.nih.gov/pubmed/29849897
http://dx.doi.org/10.1155/2018/4854732