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Disruption of the Circadian Clock Alters Antioxidative Defense via the SIRT1-BMAL1 Pathway in 6-OHDA-Induced Models of Parkinson's Disease
Parkinson's disease (PD) is the second most common neurodegenerative disease and is known to involve circadian dysfunction and oxidative stress. Although antioxidative defense is regulated by the molecular circadian clock, few studies have examined their function in PD and their regulation by s...
Autores principales: | Wang, Yali, Lv, Dongjun, Liu, Wenwen, Li, Siyue, Chen, Jing, Shen, Yun, Wang, Fen, Hu, Li-Fang, Liu, Chun-Feng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932489/ https://www.ncbi.nlm.nih.gov/pubmed/29849897 http://dx.doi.org/10.1155/2018/4854732 |
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