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Analysis of ROR1 Protein Expression in Mice with Reconstituted Human Immune System Components

Receptor tyrosine kinase-like orphan receptor 1 (ROR1) is an oncofetal antigen expressed on multiple tumors and has no significant expression on normal human tissues. ROR1 is highly upregulated in chronic lymphocytic leukemia (CLL) B cells. NOD-scid IL2rg(−/−) (NSG) mice engrafted with human CD34(+)...

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Detalles Bibliográficos
Autor principal: Leung, Carol S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932492/
https://www.ncbi.nlm.nih.gov/pubmed/29850623
http://dx.doi.org/10.1155/2018/2480931