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Analysis of ROR1 Protein Expression in Mice with Reconstituted Human Immune System Components
Receptor tyrosine kinase-like orphan receptor 1 (ROR1) is an oncofetal antigen expressed on multiple tumors and has no significant expression on normal human tissues. ROR1 is highly upregulated in chronic lymphocytic leukemia (CLL) B cells. NOD-scid IL2rg(−/−) (NSG) mice engrafted with human CD34(+)...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Hindawi
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932492/ https://www.ncbi.nlm.nih.gov/pubmed/29850623 http://dx.doi.org/10.1155/2018/2480931 |