Cargando…

Highly efficient base editing in Staphylococcus aureus using an engineered CRISPR RNA-guided cytidine deaminase

Novel therapeutic means against Staphylococcus aureus infections are urgently needed due to the emergence of drug-resistant S. aureus. We report the development of a CRISPR RNA-guided cytidine deaminase (pnCasSA–BEC), enabling highly efficient gene inactivation and point mutations in S. aureus. We e...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gu, Tongnian, Zhao, Siqi, Pi, Yishuang, Chen, Weizhong, Chen, Chuanyuan, Liu, Qian, Li, Min, Han, Dali, Ji, Quanjiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Royal Society of Chemistry 2018
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932532/ https://www.ncbi.nlm.nih.gov/pubmed/29780457 http://dx.doi.org/10.1039/c8sc00637g

Ejemplares similares

CRISPR/Cas9-based Genome Editing in Pseudomonas aeruginosa and Cytidine Deaminase-Mediated Base Editing in Pseudomonas Species
por: Chen, Weizhong, et al.
Publicado: (2018)

Programmable Base Editing in Mycobacterium tuberculosis Using an Engineered CRISPR RNA-Guided Cytidine Deaminase
por: Ding, Xin-Yuan, et al.
Publicado: (2021)

CRISPR-Cas9-Based Genome Editing and Cytidine Base Editing in Acinetobacter baumannii
por: Wang, Yu, et al.
Publicado: (2020)

Genetic Modulation of RNA Splicing with a CRISPR-Guided Cytidine Deaminase
por: Ma, Yunqing, et al.
Publicado: (2020)

A bacterial cytidine deaminase toxin enables CRISPR-free mitochondrial base editing
por: Mok, Beverly Y., et al.
Publicado: (2020)

Targeted Base Editing via RNA-Guided Cytidine Deaminases in Xenopus laevis Embryos
por: Park, Dong-Seok, et al.
Publicado: (2017)

Programmable Single and Multiplex Base-Editing in Bombyx mori Using RNA-Guided Cytidine Deaminases
por: Li, Yufeng, et al.
Publicado: (2018)

Human APOBEC1 cytidine deaminase edits HBV DNA
por: Gonzalez, Minerva Cervantes, et al.
Publicado: (2009)

Expanding C–T base editing toolkit with diversified cytidine deaminases
por: Cheng, Tian-Lin, et al.
Publicado: (2019)

Increasing the genome-targeting scope and precision of base editing with engineered Cas9-cytidine deaminase fusions
por: Kim, Y. Bill, et al.
Publicado: (2017)

APOBEC3A cytidine deaminase induces RNA editing in monocytes and macrophages
por: Sharma, Shraddha, et al.
Publicado: (2015)

Highly efficient base editing in bacteria using a Cas9-cytidine deaminase fusion
por: Zheng, Ke, et al.
Publicado: (2018)

Structure of Staphylococcus aureus cytidine monophosphate kinase in complex with cytidine 5′-monophosphate
por: Dhaliwal, Balvinder, et al.
Publicado: (2006)

Deaminase-Independent Inhibition of Parvoviruses by the APOBEC3A Cytidine Deaminase
por: Narvaiza, Iñigo, et al.
Publicado: (2009)

Robustly improved base editing efficiency of Cpf1 base editor using optimized cytidine deaminases
por: Chen, Siyu, et al.
Publicado: (2020)

Targeted In Vivo Mutagenesis in Yeast Using CRISPR/Cas9 and Hyperactive Cytidine and Adenine Deaminases
por: Skrekas, Christos, et al.
Publicado: (2023)

Unravelling the physiological roles of mazEF toxin–antitoxin system on clinical MRSA strain by CRISPR RNA-guided cytidine deaminase
por: Jain, Sonia, et al.
Publicado: (2022)

The fallout from crossing paths with cellular cytidine deaminases
por: Wain-Hobson, Simon, et al.
Publicado: (2009)

Intrinsic immunity against retrotransposons by APOBEC cytidine deaminases
por: Koito, Atsushi, et al.
Publicado: (2013)

A putative antiviral role of plant cytidine deaminases
por: Martín, Susana, et al.
Publicado: (2017)

A new technique for the analysis of metabolic pathways of cytidine analogues and cytidine deaminase activities in cells
por: Ligasová, Anna, et al.
Publicado: (2023)

An Engineered Cytidine Deaminase for Biocatalytic Production of a Key Intermediate of the Covid-19 Antiviral Molnupiravir
por: Burke, Ashleigh J., et al.
Publicado: (2022)

The double-domain cytidine deaminase APOBEC3G is a cellular site-specific RNA editing enzyme
por: Sharma, Shraddha, et al.
Publicado: (2016)

Activation-induced Cytidine Deaminase in B Cell Immunity and Cancers
por: Park, Seok-Rae
Publicado: (2012)

Cytidine deaminase activity increases in the blood of breast cancer patients
por: Buhagiar-Labarchède, Géraldine, et al.
Publicado: (2022)

The APOBEC3B cytidine deaminase is an adenovirus restriction factor
por: Lejeune, Noémie, et al.
Publicado: (2023)

Activation induced cytidine deaminase: An old friend with new faces
por: Çakan, Elif, et al.
Publicado: (2022)

Associations between activation-induced cytidine deaminase/apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like cytidine deaminase expression, hepatitis B virus (HBV) replication and HBV-associated liver disease (Review)
por: HE, XIUTING, et al.
Publicado: (2015)

Synthesis of a bifunctional cytidine derivative and its conjugation to RNA for in vitro selection of a cytidine deaminase ribozyme
por: Rublack, Nico, et al.
Publicado: (2014)

Genetic Editing of HBV DNA by Monodomain Human APOBEC3 Cytidine Deaminases and the Recombinant Nature of APOBEC3G
por: Henry, Michel, et al.
Publicado: (2009)

Interleukin-1 and Tumor Necrosis Factor-α Trigger Restriction of Hepatitis B Virus Infection via a Cytidine Deaminase Activation-induced Cytidine Deaminase (AID)
por: Watashi, Koichi, et al.
Publicado: (2013)

Engineering and optimising deaminase fusions for genome editing
por: Yang, Luhan, et al.
Publicado: (2016)

AID/APOBEC-like cytidine deaminases are ancient innate immune mediators in invertebrates
por: Liu, Mei-Chen, et al.
Publicado: (2018)

Maize haplotype with a helitron-amplified cytidine deaminase gene copy
por: Xu, Jian-Hong, et al.
Publicado: (2006)

Critical role of activation induced cytidine deaminase in Experimental Autoimmune Encephalomyelitis
por: Sun, Yonglian, et al.
Publicado: (2013)

Activation-Induced Cytidine Deaminase Does Not Impact Murine Meiotic Recombination
por: Cortesao, Catarina S., et al.
Publicado: (2013)

Characterization of immunoglobulin mutations in humans with activation-induced cytidine deaminase deficiency
por: Longo, Nancy S, et al.
Publicado: (2007)

LINE-1 Retroelements Complexed and Inhibited by Activation Induced Cytidine Deaminase
por: Metzner, Mirjam, et al.
Publicado: (2012)

Epigenetic Function of Activation-Induced Cytidine Deaminase and Its Link to Lymphomagenesis
por: Dominguez, Pilar M., et al.
Publicado: (2014)

Phosphorylation promotes activation-induced cytidine deaminase activity at the Myc oncogene
por: Mu, Yunxiang, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_3ou3j0eothdfd8u14ga98mdj8f