Cargando…

MicroRNA Silencing by DNA Methylation in Human Cancer: a Literature Analysis

MicroRNAs (miRNAs) are small non-coding RNAs that post-transcriptionally regulate the expression of target mRNAs. MicroRNA genes themselves are regulated through epigenetic mechanisms, such as histone modifications and/or DNA methylation of CpG islands. Aberrant CpG island methylation patterns are f...

Descripción completa

Detalles Bibliográficos
Autores principales: Strmsek, Ziga, Kunej, Tanja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932538/
https://www.ncbi.nlm.nih.gov/pubmed/29861414
http://dx.doi.org/10.3390/ncrna1010044