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MicroRNA Silencing by DNA Methylation in Human Cancer: a Literature Analysis
MicroRNAs (miRNAs) are small non-coding RNAs that post-transcriptionally regulate the expression of target mRNAs. MicroRNA genes themselves are regulated through epigenetic mechanisms, such as histone modifications and/or DNA methylation of CpG islands. Aberrant CpG island methylation patterns are f...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932538/ https://www.ncbi.nlm.nih.gov/pubmed/29861414 http://dx.doi.org/10.3390/ncrna1010044 |